Herpes simplex virus type 1 (HSV-1) infection dramatically remodels the host cell's nuclear structures. Infection leads to ...

Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, ...

For decades, biology textbooks have drawn a firm line: viruses are not alive. They lack the machinery to reproduce on their own, they carry no metabolism, and they depend entirely on host cells to ...

A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible for ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

Researchers found that Herpes simplex virus type 1 reorganizes nuclear speckles, essential sites for RNA processing. Without intact speckles, viral messenger RNAs cannot exit the nucleus, limiting ...

Researchers at Baylor College of Medicine report in Science Advances a breakthrough in human norovirus (HuNoV) research. Norovirus is a leading cause of acute viral gastroenteritis worldwide with ...