Paroxysmal nocturnal hemoglobinuria (PNH) means that red blood cells break down before they should. This can lead to chronic, highly individual effects that often include bloody urine, anemia, and ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder that causes red blood cells to break down. This can lead to symptoms and complications ranging from discoloration of urine to leukemia and ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, severe, and potentially life-threatening condition. Treatments targeting the complement pathway have revolutionized its management but have ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, progressive, multi-system, life-threatening disease, and diagnosing it early in the clinical course is essential for optimizing management ...

Hemolysis is a common pathophysiologic process. It occurs in numerous conditions, including genetic hemoglobinopathies and malaria, the transfusion of stored red blood cells, and during therapeutic ...

Please provide your email address to receive an email when new articles are posted on . NEW ORLEANS — Patients with paroxysmal nocturnal hemoglobinuria who received iptacopan vs. standard therapy had ...

Clone size and symptom burden dictate how often patients with PNH require follow-up. Hematology assessments during routine visits should include flow cytometry, CBC, D-dimer levels, and serum ferritin ...

Post hoc analyses of the phase 3 PEGASUS trial found that clinical and hematological improvements were associated with better patient-reported fatigue and physical function outcomes in paroxysmal ...

We have recently had the opportunity of studying a case of march hemoglobinuria in a young woman in whom attacks were precipitated by short walks. The present communication describes the clinical and ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease characterized by chronic complement-mediated hemolysis. C5 inhibition controls intravascular hemolysis in untreated PNH but cannot ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disease in which changes in stem cells within the bone marrow prompt red blood cells to break apart. This deprives the body of the normal flow ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare immune disease that causes your body to break down red blood cells when it should not. This disorder happens when there is a problem with certain ...