Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Genome editing is a powerful biotechnology tool that allows scientists to make precise changes to an organism's DNA. It involves the use of specialized enzymes, known as engineered nucleases or ...

Genetic modification once belonged strictly to science fiction, but it’s rapidly becoming reality. Scientists can now alter ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

The prime editor is a fusion protein consisting of a catalytically impaired Cas9 nickase (Cas9n) and an engineered reverse transcriptase (RT). The Cas9n is guided by a prime editing guide RNA (pegRNA) ...

A committee-supported project or activity that has been completed and for which output dissemination has begun. Its committee has been disbanded and closeout procedures are underway. An ad hoc ...

Genetic regulation of glucose homeostasis is central to the maintenance of human health and the prevention of metabolic disorders such as type 1 and type 2 diabetes. Recent advances in molecular ...

Researchers at The Jackson Laboratory and Trudeau Institute have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development, ...

"Wider, appropriate and long-term application of genetic improvement in aquaculture, with a focus on selective breeding, will help boost food production to meet a projected increase in demand for fish ...

An ad hoc committee appointed by the National Academies to explore heritable genetic modifications of food animals. This committee will address methods for heritable genetic modifications and identify ...