This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

Chemists have developed a straightforward method to convert common chemicals like carboxylic acids, alcohols, and alkanes directly into valuable alkenes. Chemists from the National University of ...

It’s a common enough scenario in many synthesis labs: you know what starting material you have, and you know what product you need but not quite what reaction conditions will get you there. Unless you ...

Chemistry is all around us. From the widespread production of global food supplies to the metabolism that fuels the tiniest of microorganisms, everything in our surroundings is produced and controlled ...

The article provides a comprehensive review of the current progress and future prospects of high-pressure-driven chemical synthesis, offering constructive guidance for the design and development of ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...

There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...

There’s an old saying about a dollar waiting on a dime. In other words, a monumental endeavor may become stuck at some point if a key preliminary element remains unavailable. The saying could be ...

It has been almost a quarter-century since K. Barry Sharpless, M.G. Finn, and Hartmuth C. Kolb published the paper that some refer to as the click manifesto. In it, the researchers presented a vision ...